Racial and Ethnic Differences in Mortality Among Hispanics Diagnosed with Follicular Lymphoma and CLL

Research indicates that Hispanic patients with diffuse large B-cell lymphoma (DLBCL) have better survival than non-Hispanic Whites; however, less is known about racial/ethnic survival differences in follicular lymphoma (FL) and chronic lymphocytic leukemia (CLL). A study published in Cancer Causes and Control sought to elucidate these differences.

Researchers identified incident FL and CLL cases diagnosed between 2005 and 2016 in the Bronx, NY. Cox proportional hazards regression was used to discern the link between race/ethnicity and all-cause mortality among FL and CLL separately. Overall, the analysis consisted of 201 FL patients, 39.3% of whom were non-Hispanic White, 19.4% who were non-Hispanic Black, and 41.3% who were Hispanic, with a similar distribution among CLL patients.

The results showed that subsequent to adjusting for International Prognostic Index factors, sex, and chemotherapy, Hispanic patients with FL had lower all-cause mortality compared to White counterparts (hazard ratio=0.22; 95% confidence interval 0.08-0.63), similar to prior DLBCL findings. The researchers noted that all-cause mortality did not differ between Black and White patients for FL or by any race/ethnicity for CLL.

In our diverse, urban population, we found that Hispanic diagnosed with FL had lower all-cause mortality compared to non-Hispanic Whites. We found no significant difference in all-cause mortality between Hispanics and non-Hispanic Whites diagnosed with CLL,” the researchers concluded. They further said that the finds add “to the growing literature on racial and ethnic differences in survival among Hispanics with hematologic malignancies.”